Table of Contents
1. So… What Is Cannabis, Really?
Welcome to this brief cannabis 101 guide. Cannabis is a flowering plant that’s been used by humans for centuries—for medicine, ritual, relaxation, and recreation. You might also know it as weed, marijuana, bud, ganja, Mary Jane, or herb. Scientifically, cannabis belongs to the Cannabaceae family and typically comes in three classifications: Cannabis sativa, Cannabis indica, and Cannabis ruderalis. The first two are the most commonly cultivated for human consumption.
But what really sets cannabis apart is its complex mix of naturally occurring compounds called cannabinoids, most famously THC (tetrahydrocannabinol) and CBD (cannabidiol). Together with aromatic oils called terpenes, they give cannabis its wide range of effects and flavors.
Note: Cannabis laws vary depending on your state and country. In Massachusetts, adult-use cannabis is legal for individuals 21 and older, but consumption is still restricted to certain private spaces.
2. How Cannabis Affects the Body and Mind
To understand how cannabis works, we need to look at the endocannabinoid system (ECS). This is a network of receptors found throughout your brain and body that helps regulate balance—think mood, appetite, pain, sleep, and memory. Your body actually makes its own cannabinoids (called endocannabinoids), but cannabis plugs into the same system with its plant-based compounds (phytocannabinoids).
THC binds strongly to receptors in the brain, producing that classic “high”—euphoria, altered time perception, increased sensory awareness, or, sometimes, couch-lock. CBD, on the other hand, doesn’t get you high. It modulates the effects of THC and is known for its calming, anti-inflammatory, and pain-relieving properties.
The exact effects of cannabis can vary based on:
- Your body’s chemistry
- The strain’s cannabinoid and terpene profile
- How much you consume
- How you consume it
- Your environment and mindset
Of course, research is ongoing and we continue to learn more about cannabis and its affects on the mind, body, and soul.
3. Benefits of Cannabis
Cannabis has been used therapeutically for millennia, and modern science is catching up. Some of the most well-supported benefits include:
✓ Pain Relief
Cannabis is widely used to manage chronic pain, arthritis, migraines, and nerve conditions.
✓ Anxiety and Stress Reduction
CBD-dominant strains may help with anxiety, though THC can sometimes increase it in high doses.
✓ Sleep Support
Certain strains can help users fall asleep faster or stay asleep longer.
✓ Appetite Stimulation
Often helpful for people undergoing chemotherapy or with appetite loss due to medical conditions.
✓ Anti-Inflammatory Properties
Both THC and CBD have been shown to reduce inflammation, potentially benefiting autoimmune disorders.
Some users also find cannabis enhances creativity, fosters introspection, or brings a sense of peace and spiritual connection.
4. THC, CBD, and Terpenes – What’s the Difference?
THC (Tetrahydrocannabinol)
The psychoactive powerhouse. THC gives you that traditional “high”—and it also carries medical benefits such as pain relief, anti-nausea effects, and muscle relaxation.
CBD (Cannabidiol)
Non-psychoactive, but deeply therapeutic. CBD is used to reduce anxiety, inflammation, and even seizures in conditions like epilepsy.
Terpenes
Terpenes are aromatic oils found in many plants (like citrus or lavender), and they give cannabis its unique smell and flavor. More importantly, terpenes interact with cannabinoids to influence how a strain makes you feel.
Some common terpenes:
- Myrcene (earthy, relaxing)
- Limonene (citrusy, uplifting)
- Linalool (floral, calming)
- Pinene (piney, alertness-enhancing)
Together, cannabinoids and terpenes work synergistically in what’s called the entourage effect—a combined outcome greater than the sum of its parts.

5. Indica vs. Sativa vs. Hybrid – Does It Still Matter?
Once upon a time, cannabis was simply split into two categories:
- Indica = Relaxing, body-high, “in-da-couch”
- Sativa = Energizing, cerebral, social
Today, most strains are hybrids, and effects depend more on the specific cannabinoid and terpene profile than the plant’s shape or label. Still, the old classification helps users estimate what they might experience—just take it with a grain of keef.
Some dispensaries now offer effect-based categories like “Sleep,” “Focus,” “Creativity,” or “Relief.” These can be more helpful when choosing a product.
6. Popular Strains and What to Expect (Massachusetts Focus)
Massachusetts dispensaries offer a wide variety of strains, including:
- Gelato (Balanced hybrid – euphoria and relaxation)
- Blue Dream (Sativa-dominant hybrid – creative, calm)
- GMO Cookies (Indica – deeply relaxing and sedating)
- Runtz (Balanced – flavorful, happy, social)
Every batch may vary, so always check the label for THC percentage, dominant terpenes, and type of experience listed.
7. Male vs. Female Plants
Only female cannabis plants produce the resinous flower that we consume. Male plants produce pollen but little to no THC or CBD. In commercial grows, males are usually removed unless they’re being used for breeding.
This matters because:
- Female plants = buds
- Male plants = seeds
- Hermaphrodite plants (can happen under stress) can reduce flower quality

8. Ways to Consume Cannabis
There’s more than one way to enjoy the plant. Here’s a breakdown:
Smoking
- Joints, blunts, bowls, or bongs
- Fast onset (within minutes)
- Can irritate lungs over time
Vaping
- Portable or desktop vaporizers
- Lower odor, smoother on lungs
- Quick onset
Edibles
- Brownies, gummies, chocolates, drinks
- Delayed onset (30 min–2 hours)
- Longer, stronger effects
Tinctures
- Dropped under the tongue (sublingual)
- Quick absorption (15–45 min)
- Easy to dose
Topicals
- Creams, balms, patches
- Applied to skin for localized relief
- No psychoactive effects
Dabbing (Advanced)
- Uses concentrates like wax or shatter
- Very high potency
- Not recommended for beginners
9. Cannabis 101 Safety Tips
Cannabis is relatively safe, but it’s important to:
- Start low and go slow, especially with edibles
- Avoid mixing with alcohol
- Don’t drive or operate machinery while under the influence
- Stay hydrated and eat something before consuming
- Know your limits
If someone overconsumes:
- Stay calm, hydrate, and rest
- CBD or black peppercorns may help ease anxiety
- Call a medical professional if symptoms are severe
10. Final Thoughts: Cannabis 101 and Community
Hopefully you’ve found this cannabis 101 guide to be insightful. Cannabis is more than a substance—it’s a culture, a medicine, and for many, a path to healing. Especially within historically marginalized communities, cannabis carries a layered legacy: criminalization, resistance, resilience, and now, potential equity.
As cannabis becomes more normalized, MassCanRev is here not just as a guide—but as a platform for local connection and economic empowerment. From exclusive authentic reviews to supporting equity-led dispensaries and wellness providers, we’re focused on amplifying Massachusetts voices in the space.
So whether you’re brand new or just brushing up, welcome to your cannabis journey—smarter, safer, and more intentional than ever.
Ready to explore more? Check out our directory full of Massachusetts cannabis dispensaries or our blog.
Learn about cannabis education programs in Massachusetts. Get your medical marijuana card.
Disclaimer: This content is for informational purposes only and is not intended as medical advice. Always consult a healthcare provider for personalized guidance.